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目的探讨川崎病(KD)心脏受累情况及其临床特点。方法对1997-06—2005-02住院的89例KD患儿进行心肌酶谱测定、心电图及超声心动图(UCG)检测。结果心电图改变53例;肌酸激酶-MB(CK-MB)增高32例(32/89,36·0%);UCG检查,心包积液12例(12/89,13·5%),二尖瓣病理性反流2例(2·2%),冠状动脉扩张(CAD)40例(44·9%),冠状动脉瘤(CAA)18例(20·2%),其中巨大CAA3例(3·4%)。结论KD合并心脏病变时,心肌炎最常见,心包炎次之,心瓣膜病变最少见,发生率分别为19·1%、13·5%和2·2%。
Objective To investigate the cardiac involvement and clinical features of Kawasaki disease (KD). Methods 89 cases of KD hospitalized from 1997-06-2005-02 were examined for myocardial enzymes, ECG and echocardiography (UCG). Results The electrocardiogram was changed in 53 cases. 32 cases (32/89, 36.0%) had increased creatine kinase-MB (CK-MB), 12 cases (12/89, 13.5% Two cases of mitral valve regurgitation (2.2%), 40 cases (44.9%) of coronary artery dilatation (CAD) and 18 (20.2%) cases of coronary aneurysm (CAA) 3.4%). Conclusions Myocarditis is most common in patients with KD complicated by heart disease, followed by pericarditis and heart valve disease. The incidence of heart disease is 19.1%, 13.5% and 2.2% respectively.