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目的探讨分析在新生儿细菌感染性疾病中的病原菌分布特点以及药敏情况。方法随机选取我院112例新生儿细菌感染患儿进行细菌培养及药敏检测,分析其致病菌分布情况以及药敏结果。结果在送检的112份检验标本中,检测主要菌种前3位分别为金黄色葡萄球菌26.79%、大肠埃希氏菌25.89%、肺炎克雷伯氏菌8.93%。此外,药敏检测发现青霉素-G、氨苄青霉素对常见病原菌的敏感率较低,分别为4.85%、11.11%;但丁胺卡那对常见病原菌的敏感率极高为98.10%。结论金黄色葡萄球菌、大肠埃希氏菌、肺炎克雷伯氏菌是新生儿细菌感染性疾病中常见的致病菌,且致病菌对临床常用的青霉素、氨苄青霉素等常用抗生素敏感率较低,因此,在临床中应针对性地、合理地选择敏感的抗生素治疗,从而提高新生儿细菌感染性疾病的临床疗效。
Objective To investigate the distribution of pathogenic bacteria in neonatal bacterial infections and their susceptibility. Methods 112 cases of neonatal bacterial infection in our hospital randomly selected for bacterial culture and drug susceptibility testing, analysis of the distribution of pathogenic bacteria and drug susceptibility results. Results Among the 112 samples tested, the top three strains of major strains were 26.79% of Staphylococcus aureus, 25.89% of Escherichia coli and 8.93% of Klebsiella pneumoniae. In addition, the susceptibility test found that penicillin-G, ampicillin sensitivity of common pathogens lower, respectively, 4.85%, 11.11%; but amikacin for common pathogens extremely high sensitivity of 98.10%. Conclusion Staphylococcus aureus, Escherichia coli and Klebsiella pneumoniae are common pathogenic bacteria in bacterial infectious diseases of neonates, and the sensitivity rate of pathogens to commonly used antibiotics such as penicillin and ampicillin commonly used in clinical practice is less Low, therefore, in the clinical should be targeted, rational selection of sensitive antibiotic treatment, thereby enhancing the clinical efficacy of neonatal bacterial infections.