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鉴于评估乳腺原发性鳞状细胞癌(SCC)生物学行为的研究结果不一致,也许因为大多数的研究没有考虑具体的组织学亚型,为此他们对1985~2010年间确诊的21例乳腺原发性鳞状细胞癌(SCC)进行了组织学特征和相关预后的分析。大多数肿瘤(17/21)属于中或低分化,细胞核多为高级别(15/21)。所有病例5年局部无复发生存(LRRFS)为(54±12)%,5年总生存率(OS)为(51±13)%。唯一与LRRFS有统计学意义的组织学特征是梭形细胞成分的存在:梭形细胞成分>10%的患者5年
Given the inconsistent results of studies evaluating the biological behavior of primary breast squamous cell carcinoma of the breast (SCC), perhaps because most studies did not consider specific histological subtypes, they identified 21 cases of breast progenitor Squamous cell carcinoma (SCC) was analyzed for histological features and associated prognosis. Most tumors (17/21) are moderately or poorly differentiated, and most of the nuclei are high grade (15/21). The 5-year LRRFS was (54 ± 12)% and the 5-year overall OS was (51 ± 13)% in all cases. The only histological feature that is statistically significant with LRRFS is the presence of spindle cell components: 5% of patients with spindle cell components> 10%