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目的:临床观察阿立哌唑治疗儿童孤独症与精神发育迟滞的疗效。方法:选取我院5儿童孤独症和精神发育迟滞患者50例纳入本试验研究,给予口服阿立哌唑,疗程4周。根据Conners父母量表评定,评估治疗前及治疗2、4周的情况,并观察其不良反应。结果:治疗2周后儿童品行问题、心身障碍、学习问题、冲动-多动、焦虑、多动等症状有显著改善(P<0.05)。治疗4周后改善更明显。结论:阿立哌唑能够有效的改善儿童孤独症与精神发育迟滞的多动、焦虑、冲动等症状。
Objective: To observe the curative effect of aripiprazole on children with autism and mental retardation. Methods: Fifty children with autism and mental retardation in our hospital were enrolled in this study. Aripiprazole was given orally for 4 weeks. According to the Conners Parents Scale assessment, pre-treatment and treatment of 2,4 weeks to assess the situation and observe the adverse reactions. Results: After 2 weeks of treatment, the symptoms such as behavior problems, psychosomatic impairment, learning problems, impulse-hyperactivity, anxiety and hyperactivity were significantly improved (P <0.05). After 4 weeks of treatment, the improvement is more obvious. Conclusion: Aripiprazole can effectively improve children with autism and mental retardation hyperactivity, anxiety, impulsive and other symptoms.