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目的观察心肌康颗粒对病毒性心肌炎(VMC)急性期患儿的疗效。方法选择本院2006年3月-2009年3月收治的VMC急性期患儿86例。随机分为治疗组和对照组,每组43例。均予常规治疗,治疗组在此基础上加用心肌康颗粒。分别检测二组治疗前后血CD3+、CD4+、CD8+、CD4+/CD8+、CK-MB和心肌肌钙蛋白Ⅰ(cTnⅠ)水平。结果治疗组疗效优于对照组(总有效率:86.05%vs72.09%,P=0.038)。治疗前,二组CD3+、CD4+、CD8+、CD4+/CD8+比值比较差异均无统计学意义(Pa>0.05);而治疗后二组上述指标比较差异均有统计学意义(Pa<0.05);治疗组治疗后CK-MB和cTnⅠ水平较对照组显著下降,差异有统计学意义(Pa<0.05)。结论心肌康颗粒对VMC急性期患儿有较好的治疗作用。
Objective To observe the effect of Xinjikang granule on children with acute viral myocarditis (VMC). Methods 86 patients with acute VMC in our hospital from March 2006 to March 2009 were selected. Randomly divided into treatment group and control group, 43 cases in each group. All patients were treated by conventional therapy. On the basis of this treatment, the treatment group was given XinKangKang granules. The levels of CD3 +, CD4 +, CD8 +, CD4 + / CD8 +, CK-MB and cardiac troponin Ⅰ (cTnⅠ) were measured before and after treatment in the two groups. Results The curative effect of the treatment group was better than that of the control group (total effective rate: 86.05% vs72.09%, P = 0.038). There was no significant difference in the ratio of CD3 +, CD4 +, CD8 + and CD4 + / CD8 between the two groups before treatment (Pa> 0.05), but there was significant difference between the two groups after treatment (Pa <0.05) After treatment, the levels of CK-MB and cTnⅠdecreased significantly compared with the control group (P <0.05). Conclusions Xinjikang granule has good therapeutic effect on children with acute VMC.