黑变病多与接触石油产品、煤焦油、橡胶添加剂、染料等有关[1]。我们在某焦化厂职工职业性健康查体时发现黑变病2例,报告如下:1病例资料男性患者,34岁,机焦车间作业工人,专业工龄12年。女性患者,26岁,回收车间作业工人,专业工龄8年。其皮损均始于面部,初有瘙痒、灼痛感。男性患 Melanosis and more contact with petroleum products, coal tar, rubber additives, dyes, etc. [1]. We found a coking plant workers in occupational health examination revealed two cases of black disease, the report is as follows: 1 case information male patients, 34 years old, machine shop workers, professional 12-year service. Female patient, 26 years old, recycle shop worker, professional 8 years of service. The lesions are from the face, the first itching, burning sensation. Male suffering