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目的观察亲水性纤维含银敷料(Aquacel-Ag)治疗深Ⅱ度烧伤创面的疗效。方法深Ⅱ度烧伤患者60例随机均分为两组,在常规治疗的基础上,A组创面采用Aquacel-Ag处理,B组用磺胺嘧啶银霜处理。观察至创面愈合或用药4周,比较两组创面换药疼痛程度和创面愈合时间,计算14、20和28d创面愈合率,评估抗感染效果及安全性。结果与B组比较,A组换药时疼痛程度轻、愈合时间早(P<0.05)。A组无细菌培养阳性病例;B组7例次细菌培养阳性。用药4周内,两组患者及创面均未见明显不良反应。结论 Aquacel-Ag治疗深Ⅱ度烧伤创面疗效确切,无明显不良反应。
Objective To observe the curative effect of Aquacel-Ag on deep second degree burn wounds. Methods Sixty patients with deep second degree burn were randomly divided into two groups. On the basis of routine treatment, group A was treated with Aquacel-Ag and group B with silver sulfadiazine. The wounds were observed and wound healing or medication for 4 weeks. The degree of dressing change and wound healing time were compared between the two groups. The wound healing rates at 14, 20 and 28 days were calculated to evaluate the anti-infective effect and safety. Results Compared with group B, the pain in group A was lighter and the healing time was earlier (P <0.05). A group without bacterial culture positive cases; B group 7 cases of bacterial culture positive. Within 4 weeks after treatment, no obvious adverse reactions were found in both patients and wounds. Conclusion Aquacel-Ag treatment of deep second degree burn wounds curative effect is exact, no obvious adverse reactions.