论文部分内容阅读
目的探讨高空环境对飞行人员骨密度和骨代谢指标的影响,分析飞行人员骨密度和骨代谢水平与飞行时间的关系。方法某航空公司健康男性飞行员139名(20~60岁)和健康地面男性对照人员37名(20~60岁),按照年龄分成4组:20~年龄组,30~年龄组,40~年龄组,50~60年龄组,分别采用单光子超远端两维骨密度测量法测量骨密度,放射免疫分析法测定血清骨钙素(BGP)水平,采用酶联免疫分析法测定血清骨特异性碱性磷酸酶(BALP),其结果用组间t检验进行比较,各变量与飞行时间之间进行相关分析。结果飞行员各年龄段骨密度均值水平均低于正常值,P<0.05;50～60岁年龄组尺骨BMD明显低于正常组,P<0.05。尺骨的BMD受飞行年限的影响较桡骨敏感。飞行人员BGP水平和BALP水平均低于对照组,飞行人员BGP水平和BALP水平与对照组比较,在20~年龄组和30~年龄组均显著降低(P<0.01),40~年龄组之间差异无显著性(P>0.05),与累积飞行时间呈显著性负相关(P<0.01)。结论高空环境能降低飞行员的骨密度,尺骨受高空环境的影响较桡骨敏感。并影响飞行人员的骨代谢水平,且与飞行时间相关。
Objective To investigate the effects of altitude environment on the bone mineral density and bone metabolic parameters of pilots and to analyze the relationship between the bone mineral density and bone metabolism level and the flight time of pilots. Methods A total of 139 healthy male pilots (20-60 years old) and 37 healthy male ground controls (20-60 years old) were divided into 4 groups according to their ages: 20 ~ 30 years old, 40 ~ , 50 ~ 60 age group, bone mineral density (BMD) was measured by single-photon ultra-distal two-dimensional bone mineral density measurement, radioimmunoassay was used to measure the level of serum BGP, ELISA was used to detect serum bone- The results were compared between groups using t-test and correlation analysis between variables and time-of-flight. Results The average BMD of pilots was lower than normal at all ages (P <0.05). BMD of ulna in 50-60 age group was significantly lower than that in normal group (P <0.05). The BMD of ulna is more sensitive to radius than that of flight. The level of BGP and the level of BALP in pilots were lower than those in control group. The levels of BGP and BALP in pilots were significantly lower (P <0.01) between the age of 20 ~ 30 and the age of 40 ~ There was no significant difference (P> 0.05), but significant negative correlation with cumulative flight time (P <0.01). Conclusion The high-altitude environment can reduce the pilot’s bone density. The ulna is more sensitive to radius than the high-altitude environment. And affect the flight crew’s bone metabolism level, and with the time of flight.