目的 synergium(一个协同合作论坛)致力于设计和优化促进卒中发展的新途径,以降低卒中风险、影响及后果。方法由卒中学术带头人组成的7个工作组及其引领的约由100名参与者组成的synergium论坛共同完成前期工作。结论性草案文件由论坛外的撰稿者进一步录入整理。结果 synergium论坛的建议如下:(1)基础科学、药物开发及技术:①致力于突破流行的僵化思维(silo mentality)的新体系;②将基础、临床、流行病学学科纵向融合的新模式;⑤确立其他相关科学领域的有效方法。(2)卒中预防:①制定将卒中作为主要重点的全球慢性疾病预防方案;②认识到不仅是猝然发病的卒中,隐匿的亚临床卒中以及最普通的脑血管疾病的类型都会导致功能缺损;③制定、完善并评估族群卒中预防的方法;④应用传统技术或新技术(如社会传媒/营销),开发公共卫生通讯战略。(3)急性卒中的处理:继续建立卒中中心,卒中单元,急诊卒中医疗的区域体系,卒中电视网络。(4)脑恢复及康复:①将最好的动物及人类实验研究领域的神经科学转化为卒中后康复研究及临床医疗;②将卒中后康复依照最佳证据标准化;⑤对标准的临床和替代评估形成共识并实施;④为改善卒中康复实施严格的临床研究。(5)进入21世纪,重视网络、科技及通信的应用:①致力于卒中相关信息的全球无限制访问;②建立集中的电子档案库及登记库。(6)发展利益相关方的合作(大型卒中机构、非政府组织、政府、患者机构及行业),改善卒中医疗。(7)教育并激励同行、患者、公众、政策制定者使用“脑健康’的概念,以普及预防措施。结论为加速卒中的发展,我们必须从科学、理论以及实际的角度出发超越现状。我们不仅要努力进步,也要停止错误。停止未经证实的观点、未经验证的方法及经济利益驱使的实践可以显著节省时间、财力及人力。将知识系统地融入项目中,加之详实的评估可以加速前进的步伐。 Purpose synergium, a collaborative forum, is devoted to designing and optimizing new avenues for the promotion of stroke to reduce the risk, impact and consequences of stroke. Methods Seven working groups composed of stroke academic leaders and the synergium forum led by about 100 participants completed the preliminary work. The concluding document is further edited by contributors outside the forum. Results The recommendations of the Synergium Forum are as follows: (1) Basic science, drug development and technology: ① A new system dedicated to breaking the popular silo mentality; ② A new paradigm of vertical integration of basic, clinical and epidemiological disciplines; ⑤ establish other relevant scientific fields of effective methods. (2) Stroke Prevention: (1) Develop a global program for the prevention of chronic diseases with stroke as the main focus; (2) Recognize that not only sudden onset of stroke, occult subclinical stroke, and the most common type of cerebrovascular disease cause functional impairment; Develop, refine and assess ethnic stroke prevention methods. Develop traditional strategies for public health communication using traditional or new technologies such as social media / marketing. (3) Treatment of Acute Stroke: Continue to establish a stroke center, a stroke unit, a regional system for emergency medical care for stroke, and a network of stroke television networks. (4) Brain Recovery and Rehabilitation: (1) Transforming the best neuroscience in animal and human experimental research into post-stroke rehabilitation research and clinical care; (2) Standardizing post-stroke rehabilitation in accordance with best evidence; (5) Assessment consensus and implementation; ④ to improve stroke rehabilitation to implement rigorous clinical research. (5) Entering the 21st century, emphasis should be placed on the application of network, technology and communications: ① Unrestricted global access to information related to stroke; ② Establishment of centralized electronic archives and registries. (6) To develop stakeholder cooperation (large stroke institutions, NGOs, governments, patient agencies and industries) to improve stroke care. (7) Educate and motivate peers, patients, the public, and policymakers to use the concept of ”brain health" to popularize preventive measures.Conclusion To accelerate the development of stroke, we must surpass the status quo from a scientific, theoretical, and practical point of view. Not only must we work hard to make progress, we must stop our mistakes. Stopping unverified ideas, unverified methods and financially driven practices can significantly save time, money and manpower. Integrating knowledge into the project, coupled with detailed assessments Can accelerate the pace of progress.