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采用家兔失血性休克／再灌注模型（Ｓ／Ｒ），观察损伤后血浆中一氧化氮（ＮＯ）终代谢产物的改变及磷脂酶Ａ＿２阻断剂氯喹及其同类合成药磷酸萘酚喹、抗氧化剂黄芪酮治疗对其的影响。结果表明Ｓ／Ｒ后２４ｈ内血浆含量逐渐下降同血ｐＨ值及二氧化碳结合力ＴＣＯ＿２下降有正相关；应用磷脂酶Ａ＿２阻断剂和抗氧化剂可在一定程度上阻断的减少，且对维持体内酸碱平衡有一定作用。
Rabbit hemorrhagic shock / reperfusion model (S / R) was used to observe the changes of NO in serum and the changes of the final metabolites of NO and the phospholipase A 2 blockers chloroquine and its analogues naphthoquine, Effect of Antioxidant Astragaloside on It. The results showed that within 24 hours after S / R, the decrease of plasma concentration was positively correlated with the decrease of blood pH and carbon dioxide binding capacity (TCO 2). The decrease of phospholipase A 2 blockers and antioxidants could be blocked to a certain extent, Acid-base balance has a role.