From a perspective of Chinese medicine(CM), persons with unregulated “unhealthy” body constitution(BC) will further develop chronic diseases, such as diabetes mellitus(DM). Conventional dietary therapy with nutrition component has its limitations in the regulation of “unhealthy” BC. However, empirical evidence supports that “unhealthy” BC can be regulated with food natures and fl avors from a perspective of CM. Presentations of “unhealthy” BC types, such as Yin-deficiency, Yang-deficiency and Yin-Yang deficiency were found in persons with DM. It would be necessary to regulate the “unhealthy” BC presentations with integration of conventional dietary therapy and Chinese food therapy. The ultimate goal is to either stabilize glycaemic control or prevent the development of other chronic diseases leading to reduction of disease burden, such as disease-related poor quality of life, stress of healthcare professionals and the rising of healthcare cost. From a perspective of Chinese medicine (CM), persons with unregulated “unhealthy” body constitution (BC) will further develop chronic diseases, such as diabetes mellitus (DM). Conventional dietary therapy with nutrition component has its limitations in the regulation of “unhealthy ” BC. However, the empirical evidence supports that “unhealthy ” BC can be regulated with food natures and fl avors from a perspective of CM. Presentations of “unhealthy ” BC types, such as Yin- Yang-deficiency and Yin-Yang deficiency were found in persons with DM. It would be necessary to regulate the “unhealthy” BC presentations with integration of conventional dietary therapy and Chinese food therapy. The ultimate goal is to either stabilize glycaemic control or prevent the development of other chronic diseases leading to reduction of disease burden, such as disease-related poor quality of life, stress of healthcare professionals and the rising of healthcare costs.