乙型肝炎病毒的传播已成为重要的世界性健康问题。我国是乙肝的流行高发区 ,据报道ＨＢｓＡｇ阳性占总人口的10 %。[1] 母婴传播是乙肝病毒 (ＨＢＶ)的重要传播途径 ,程蔚[2 ]报道母婴传播率为 83 .3% ,而当母亲ＨＢｓＡｇ及ＨＢｅＡｇ双阳性者 ,母婴传播率达 92 %～ 97%。[3] The spread of hepatitis B virus has become an important worldwide health problem. China is a high prevalence area of ​​hepatitis B. It is reported that HBsAg positive accounts for 10% of the total population. [1] Maternal-to-infant transmission is an important transmission route of hepatitis B virus. Cheng et al. [2] reported a mother-to-child transmission rate of 83.3%. However, when maternal HBsAg and HBeAg were double positive, the mother-to-child transmission rate reached 92% ~ 97%. [3]