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免疫耐受并非是器官移植领域特有的的现象,而是免疫学领域的普遍现象。本文强调“大量的移植抗原能够诱导宿主免疫系统特异性的免疫细胞凋亡以及造成细胞因子、抗体等免疫物质耗竭”是免疫耐受形成的一个重要原因,以此对许多免疫耐受现象进行解释,并从这个角度推断“在器官移植前后通过大量抗原诱导同种、异种器官移植形成免疫耐受”。
Immune tolerance is not a peculiar phenomenon in the field of organ transplantation, but a universal phenomenon in the field of immunology. This article emphasizes that “a large number of transplanted antigens can induce immune cell-specific immune cell apoptosis in host immune system and result in depletion of immune substances such as cytokines and antibodies”, which is an important reason for the formation of immune tolerance and thus explain many immune tolerance phenomena , And concluded from this perspective that “allogeneic organ transplantation can induce immune tolerance by inducing a large number of antigens before and after organ transplantation”.