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目的观察盐酸西替利嗪治疗咳嗽变异性哮喘临床疗效。方法选择60例咳嗽变异性哮喘患者随机分为2组,治疗组每晚服用盐酸西替利嗪10mg,1次/d,对照组每晚服用酮替芬1mg,1次/d,分别于病程的7～10d,25～30d观察两组的疗效。结果两组患者在分别治疗7～10d及25～30d后疗效比较差异有统计学意义(P<0.05)。治疗组在7～10d及25～30d的行平均分-f1均大于对照组的行平均分。因此治疗组即加用盐酸西替利嗪组的疗效明显好于对照组。结论联用盐酸西替利嗪治疗咳嗽变异性哮喘起效快、效果确切,不良反应小。
Objective To observe the clinical efficacy of cetirizine hydrochloride in the treatment of cough variant asthma. Methods Sixty patients with cough variant asthma were randomly divided into two groups. The treatment group took cetirizine hydrochloride 10 mg once daily, while the control group took ketotifen 1 mg once daily, Of 7 ~ 10d, 25 ~ 30d observed the efficacy of both groups. Results The two groups of patients in the treatment of 7 ~ 10d and 25 ~ 30d after the difference was statistically significant (P <0.05). The mean score -f1 of the treatment group at 7-10 days and 25-30 days was greater than that of the control group. Therefore, the treatment group that is treated with cetirizine hydrochloride group was significantly better than the control group. Conclusions The combination of cetirizine hydrochloride for cough variant asthma has rapid onset, definite effect and small adverse reaction.