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本文对41例慢性肾衰血透患者和17例接受移植肾患者的血清脂蛋白和载脂蛋白水平进行了研究。结果表明,血透病人组HDL-C、HDL_2-C 和apoA-I 明显低子对照组,apoA-I/HDL-C 明显增加,尤其在伴有心血管并发症组更加明显。提示HDL-C 量和质的改变在动脉粥样硬化的进展中超重要作用。肾移植组HDL_3-C 和LDL-C 增加显著;HDL-C 和apoA-I 水平亦明显高于对照组和血透组,且二者呈正相关。但尚不能排除使用激素和/或环孢素影响的可能性。
In this paper, 41 patients with chronic renal failure and 17 patients with renal transplant recipients of serum lipoprotein and apolipoprotein levels were studied. The results showed that HDL-C, HDL-2-C and apoA-I significantly low hematopoietic group control group, apoA-I / HDL-C increased significantly, especially in patients with cardiovascular complications more obvious. Suggesting that changes in the amount and quality of HDL-C play an important role in the development of atherosclerosis. The levels of HDL-3-C and LDL-C in kidney transplantation group were significantly increased, and the levels of HDL-C and apoA-I in kidney transplantation group were also significantly higher than those in control group and hemodialysis group. However, the possibility of using hormone and / or cyclosporine can not be ruled out.