癫痫与肠腔疾病关系的报导已不新鲜。在1960年,Cooke与Smith描述了5例意识丧失不能解释的病人,12年后,Chapman等报导5.5％肠腔病人存在癫痫:其中77％癫痫病人为现在所谓的部分性癫痫。尽管个案病例报告于1976年描述,但特定综合征的存在,包括颅内钙化及肠腔疾病和部分性癫痫则由Sammaritano于1988年首次提出。在最大规模研究中,癫痫及钙化病人通过小肠活检从肠腔病中筛选出来,31例中77％病人有绒毛萎缩。相反在12例患肠腔病及癫痫患者中,42％CT扫描有钙化。对 Epilepsy and intestinal diseases reported no longer fresh. In 1960, Cooke and Smith described five patients who could not explain unconsciousness. Twelve years later, Chapman et al. Reported that epilepsy was present in 5.5% of intestine patients: 77% of them were now part-time epilepsy. Although case-specific reports were described in 1976, the presence of specific syndromes, including intracranial calcification and intestinal diseases, and partial epilepsy were first proposed by Sammaritano in 1988. In the largest study, patients with epilepsy and calcification were screened for intestinal disease by small bowel biopsy, and of the 31 patients, 77% had villous atrophy. In contrast, 42% of CT scans were calcified in 12 patients with enteropathy and epilepsy. Correct