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目的研究前哨淋巴结显像在宫颈癌诊断和治疗中的临床应用价值。方法对35例Ⅰa～Ⅱb期宫颈癌患者,术前行前哨淋巴结显像;术中用γ探测仪定位前哨淋巴结;术后对前哨淋巴结和非前哨淋巴结进行病理检查。结果前哨淋巴结与非前哨淋巴结病理检查结果具有很高的符合率,灵敏性83.3%,准确性97.1%,阴性预测值96.6%。结论前哨淋巴结显像检查对盆腔淋巴结肿瘤转移状况具有代表性和诊断意义,该检查用于宫颈癌的诊断和术前手术方案的选择具有科学性和可行性。
Objective To study the clinical value of sentinel lymph node imaging in the diagnosis and treatment of cervical cancer. Methods Seventy-five patients with stage Ⅰa-Ⅱb cervical cancer underwent preoperative imaging of sentinel lymph nodes. The sentinel lymph nodes were localized by γ-detector during the operation. The sentinel lymph nodes and non-sentinel lymph nodes were examined by pathology. Results The results of sentinel lymph node and non-sentinel lymph node biopsy showed a high coincidence rate of 83.3%, accuracy of 97.1% and negative predictive value of 96.6%. Conclusion The detection of sentinel lymph node imaging has a representative and diagnostic significance for the metastasis of pelvic lymph nodes. This examination is of scientific and feasibility for the diagnosis of cervical cancer and the selection of surgical options.