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目的:了解黄冈市药品不良反应/事件(ADR/ADE)的发生规律及特点,促进临床合理用药。方法:对黄冈市内10县2010年上报的1 944例ADR/ADE报告进行回顾性分析。结果:1944例ADR/ADE涉及抗微生物药957例,占49.23%,中药制剂366例,占18.83%;注射给药引起的ADR/ADE 1 447例,构成比为74.43%;ADR/ADE的临床表现以皮肤及附件最为常见,其次是消化系统损害等。结论:应加强ADR/ADE监测及相关知识宣传的力度,强化对ADR/ADE的认识并完善ADR/ADE监测体系,提高上报ADR/ADE的质量,促进临床合理用药。
Objective: To understand the rules and characteristics of adverse drug reactions / events (ADR / ADE) in Huanggang and to promote clinical rational use of drugs. Methods: A retrospective analysis was made on 1 944 ADR / ADE reports reported by 10 counties in Huanggang in 2010. Results: 1944 cases of ADR / ADE involved 957 cases of antimicrobials, accounting for 49.23%, 366 cases of traditional Chinese medicine preparations, accounting for 18.83%; ADR / ADE 1 447 cases caused by injection, the constituent ratio was 74.43%; ADR / ADE clinical The most common manifestations of skin and accessories, followed by digestive damage. Conclusion: We should strengthen the monitoring of ADR / ADE and related knowledge publicity, strengthen the understanding of ADR / ADE and improve the ADR / ADE monitoring system, improve the quality of reported ADR / ADE and promote the rational use of clinical medicine.