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《日本国际医学论坛报》第15卷第2期(1982年)报道:尽管人们一直认为乙型病毒性肝炎的发病、恶化与个体的免疫反应有关,但在肝细胞的损伤机理方面迄今仍有许多不明之处。对此,日本新泻大学第三内科的石原清等通过实验研究做了进一步的探讨,认为“作为淋巴细胞组分之一的T细胞在乙型病毒性肝炎的进展中起着重要作用”,并在东京召开的日本第十一届免疫学会议上报告了此项研究成果。将来自HBs抗原阳性的慢性肝病患者的活检组织直接进行肝细胞的分离和培养,是这次实验的一大特征。具体方法是:把1.5cm的活
“Japan International Medical Tribune, Vol. 15, No. 2 (1982) reported: Although people always think that the incidence of hepatitis B, the deterioration of the immune response and the individual, but in the liver damage mechanism so far there is still Many unknown. In this regard, Japan’s Niigata University, Department of Internal Medicine, Ishihara Shimizu et al through experimental research to further explore that ”as one of the lymphocyte components of T cells in the progress of hepatitis B plays an important role, And reported the results of the study at the 11th Japan Immunology Conference held in Tokyo. Direct isolation and culture of biopsies from patients with HBsAg-positive chronic liver disease is a hallmark of this experiment. The specific method is: to 1.5cm of live