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癌胚抗原(Carcinoembryoric Antigen,CEA)是Gold等1965年首先从结肠癌中分离出来的肿瘤相关抗原,是一组糖蛋白。目前广泛应用于上皮源性的肿瘤的研究。关于胆囊癌组织CEA研究国内未见公开报导。我们应用免疫组化技术对21例胆囊癌及癌旁粘膜作了CEA标记。通过观察CEA在胆囊癌及癌旁粘膜中分布探讨CEA在胆囊癌研究中的意义。
Carcinoembryoric Antigen (CEA) is a tumor-associated antigen first isolated from colon cancer by Gold et al. in 1965 and is a group of glycoproteins. It is widely used in studies of epithelial-derived tumors. The CEA study on gallbladder cancer tissue has not been publicly reported in China. We used immunohistochemistry to make CEA markers in 21 cases of gallbladder carcinoma and paraneoplastic mucosa. The significance of CEA in the study of gallbladder cancer was investigated by observing the distribution of CEA in gallbladder carcinoma and adjacent mucosa.