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目的：探讨Ｘ综合征和冠心病左心室功能的不同变化。方法：冠状动脉造影确诊冠心病（Ｃ组）１０例和Ｘ综合征（Ｘ组）１０例，左心导管测量两组的血流动力学参数。结果：左心室压力微分最大值，Ｘ组明显高于Ｃ组２３５．４１±２５．８９ｋＰａ／ｓ（１７７０±１９５ｍｍＨｇ／ｓ）比１８４．８７±２４．４４ｋＰａ／ｓ（１３９０±１８４ｍｍＨｇ／ｓ，Ｐ＜０．０５）；左心室压力微分最小值、时间常数、左心室舒张压最低值，Ｘ组明显低于Ｃ组（Ｐ均＜０．０５）它们分别是－２７０．６６±２１．９６ｋＰａ／ｓ（－２０３５±１６５ｍｍＨｇ／ｓ）比－１３８．９９±２１．５９ｋＰａ／ｓ（－１０４５±１６２ｍｍＨｇ／ｓ）；２４．４６±３．８０ｍｓ比５０．９５±７．１３ｍｓ；－１．８６±０．４５ｋＰａ（－１４±３ｍｍＨｇ）比１．５６±０．４４ｋＰａ（１２±３ｍｍＨｇ）。心率、左心室最大收缩压、左心室舒张末压，两组间无显著性差异（Ｐ＞０．０５）。结论：冠心病组较Ｘ综合征组影响左心室功能更明显。
Objective: To investigate the different changes of left ventricular function in syndrome X and coronary heart disease. Methods: Coronary heart disease (group C) was diagnosed by coronary angiography in 10 cases and syndrome X (group X) in 10 cases. The left cardiac catheter was used to measure the hemodynamic parameters. Results: The maximal differential value of left ventricular pressure was significantly higher in group X than in group C (235.41 ± 25.89 kPa / s (1770 ± 195 mmHg / s) vs 184.87 ± 24.44 kPa / s (1390 ± 184 mmHg / s, P <0.05). The minimum value of left ventricular pressure differential, time constant and the lowest value of left ventricular diastolic pressure were significantly lower in group X than those in group C (P <0.05). They were -270.66 ± 21.96 kPa / s (-2035 ± 165 mmHg / s) -138.99 ± 21.59 kPa / s (-1045 ± 162 mmHg / s); 24.46 ± 3.80 ms vs. 50.95 ± 7.13 ms; -1.86 ± 0.45 kPa (-14 ± 3 mmHg) to 1.56 ± 0.44 kPa (12 ± 3 mmHg). Heart rate, left ventricular systolic blood pressure and left ventricular end diastolic pressure, there was no significant difference between the two groups (P> 0.05). Conclusion: The effect of left ventricular function in coronary heart disease group is more obvious than that in syndrome group X.