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目的:探讨X综合征和冠心病左心室功能的不同变化。方法:冠状动脉造影确诊冠心病(C组)10例和X综合征(X组)10例,左心导管测量两组的血流动力学参数。结果:左心室压力微分最大值,X组明显高于C组235.41±25.89kPa/s(1770±195mmHg/s)比184.87±24.44kPa/s(1390±184mmHg/s,P<0.05);左心室压力微分最小值、时间常数、左心室舒张压最低值,X组明显低于C组(P均<0.05)它们分别是-270.66±21.96kPa/s(-2035±165mmHg/s)比-138.99±21.59kPa/s(-1045±162mmHg/s);24.46±3.80ms比50.95±7.13ms;-1.86±0.45kPa(-14±3mmHg)比1.56±0.44kPa(12±3mmHg)。心率、左心室最大收缩压、左心室舒张末压,两组间无显著性差异(P>0.05)。结论:冠心病组较X综合征组影响左心室功能更明显。
Objective: To investigate the different changes of left ventricular function in syndrome X and coronary heart disease. Methods: Coronary heart disease (group C) was diagnosed by coronary angiography in 10 cases and syndrome X (group X) in 10 cases. The left cardiac catheter was used to measure the hemodynamic parameters. Results: The maximal differential value of left ventricular pressure was significantly higher in group X than in group C (235.41 ± 25.89 kPa / s (1770 ± 195 mmHg / s) vs 184.87 ± 24.44 kPa / s (1390 ± 184 mmHg / s, P <0.05). The minimum value of left ventricular pressure differential, time constant and the lowest value of left ventricular diastolic pressure were significantly lower in group X than those in group C (P <0.05). They were -270.66 ± 21.96 kPa / s (-2035 ± 165 mmHg / s) -138.99 ± 21.59 kPa / s (-1045 ± 162 mmHg / s); 24.46 ± 3.80 ms vs. 50.95 ± 7.13 ms; -1.86 ± 0.45 kPa (-14 ± 3 mmHg) to 1.56 ± 0.44 kPa (12 ± 3 mmHg). Heart rate, left ventricular systolic blood pressure and left ventricular end diastolic pressure, there was no significant difference between the two groups (P> 0.05). Conclusion: The effect of left ventricular function in coronary heart disease group is more obvious than that in syndrome group X.