骨质疏松症是常见的老年性疾病。全球有2亿骨质疏松患者,在我国就高达9000万之多,且以绝经后妇女发病率更高,约60%~70%。妇女绝经后骨质疏松症(postmenopausalosteoporosis,PMO)防治中备受关注且疗效确切的治疗方案是雌激素替代疗法,但长期服用雌激素可诱发乳腺、卵巢、子宫肿 Osteoporosis is a common senile disease. There are 200 million osteoporosis patients in the world, as high as 90 million in China, and the incidence of postmenopausal women is higher, about 60% to 70%. In women with postmenopausal osteoporosis (PMO) prevention and treatment of concern and the curative effect of the exact treatment is estrogen replacement therapy, but long-term use of estrogen can induce breast, ovarian, uterine enlargement