论文部分内容阅读
目的 :探讨慢性乙型肝炎 (乙肝 )和活动性肝硬变肝组织病变与乙肝病毒标志物 (HBVM)和肝功能的关系。方法 :在 Knodell的乙肝肝组织炎性活性指标 (HAI)分类上采用 3次密码读片 ;用常规的方法检测血清胆红素 (SB)、丙氨酸转氨酶 (AL T)、天冬氨酸转氨酶 (AST)、白蛋白 /球蛋白 (A/ G)比率 ;肝内 HBs Ag、HBc Ag检测用PAP法。结果 :SB、AL T、AST值随 HAI记分值的增高而增高 ,慢性肝炎、活动性肝硬变患者血清 A、G的含量及A/ G也随 HAI记分值的增高而变化。结论 :HAI能客观定量的反映肝组织病变的程度 ,为疾病的诊断、治疗和预后判断提供一种实用的病理指标 ,并有利于微机图像阅片和统计学分析
Objective: To investigate the relationship between hepatitis B virus (HBV) and hepatic cirrhosis with liver cirrhosis and hepatitis B virus (HBVM) and liver function. Methods: Knodell’s hepatitis B liver tissue inflammatory activity index (HAI) classification was used to read the password 3 times. The levels of serum bilirubin (SB), alanine aminotransferase (ALT), aspartate Aminotransferase (AST), albumin / globulin (A / G) ratio; intrahepatic HBsAg, HBcAg detection by PAP method. Results: The SB, ALT and AST values increased with the increase of HAI score. The levels of serum A and G and A / G in patients with chronic hepatitis and active cirrhosis also changed with the increase of HAI score. Conclusion: HAI can objectively and quantitatively reflect the degree of liver lesion and provide a practical pathological index for the diagnosis, treatment and prognosis of the disease, and is beneficial to computer image reading and statistical analysis