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目的探讨奥曲肽对肠梗阻患者的临床治疗效果及其安全性。方法 136例肠梗阻患者,随机分为研究组和对照组,每组68例。对照组患者采用本院肠梗阻常规的方法进行治疗,研究组患者则在对照组基础上静脉注射奥曲肽进行治疗,比较两组患者的治疗效果和不良反应发生情况。结果研究组患者治疗总有效率为95.6%,高于对照组患者的77.9%,差异具有统计学意义(χ~2=9.220,P<0.05);研究组不良反应发生率为27.9%,对照组为29.4%,两组不良反应发生率比较差异无统计学意义(χ~2=0.036,P>0.05)。结论对于肠梗阻患者采用奥曲肽进行治疗,临床疗效显著,且安全性与常规治疗方法无差异,可进行推广应用。
Objective To investigate the clinical effect and safety of octreotide in patients with intestinal obstruction. Methods 136 patients with intestinal obstruction were randomly divided into study group and control group, with 68 cases in each group. Patients in the control group were treated with the conventional method of intestinal obstruction in our hospital. Patients in the study group were treated with intravenous injection of octreotide on the basis of the control group. The therapeutic effect and adverse reactions of the two groups were compared. Results The total effective rate of study group was 95.6%, which was higher than that of the control group (77.9%), the difference was statistically significant (χ ~ 2 = 9.220, P <0.05). The incidence of adverse reactions in study group was 27.9% Was 29.4%. There was no significant difference in the incidence of adverse reactions between the two groups (χ ~ 2 = 0.036, P> 0.05). Conclusion The patients with intestinal obstruction using octreotide for treatment, clinical efficacy was significant, and no difference in safety and conventional treatment methods, which can be promoted.