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测定不同时期病毒性心肌炎患儿的细胞免疫 ,以探讨其临床意义 ,将92例病毒性心肌炎患儿和30例对照组细胞免疫检测结果进行比较。结果显示 ,心肌炎急性期和慢性期的细胞免疫 (CD3、CD4、CD8和B细胞 )与对照组比较 ,差异有显著性(P<0.01) ;恢复期CD4/CD8存在显著差异 (P<0.05) ;迁延期CD4和B细胞存在显著差异。表明病毒性心肌炎免疫改变以细胞免疫为主 ,存在免疫细胞功能紊乱 ,于急性期及慢性期尤为显著 ,恢复期好转 ,迁延期存在T细胞亚类比例失衡
To determine the cellular immunity of children with viral myocarditis at different stages in order to explore its clinical significance. The results of cellular immunity in 92 children with viral myocarditis and 30 controls were compared. The results showed that the cellular immunity (CD3, CD4, CD8 and B cells) in acute and chronic myocarditis was significantly different from that in control group (P <0.01), while there was significant difference in recovery CD4 / CD8 (P <0.05) There was a significant difference in CD4 and B cell proliferation between the two groups. The results showed that the immune changes of viral myocarditis were mainly cellular immunity with immune cell dysfunction, especially in acute phase and chronic phase. The recovery period improved, and there was imbalance of T cell subsets in the delayed phase