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目的:对比分析晚期早产儿及正常足月儿间神经发育情况的差异,探讨影响晚期早产儿神经发育异常的相关因素。方法:以我院妇产科分娩成功的晚期早产儿134例及同期正常分娩足月儿100例为研究对象,统计他们的一般资料并进行发育商测试,采用Logistic回归分析筛选影响晚期早产儿神经发育的危险因素。结果:除适应性及社会行为两项外,晚期早产儿组的大运动、精细动作、语言评分及DQ评分均显著降低(P<0.05);晚期早产儿组出现神经发育异常者9例,发生率为6.72%,较对照组(1.00%)显著升高(P<0.05);晚期早产儿神经发育异常与极低出生体重、低血糖、母亲文化程度低密切相关。结论:晚期早产儿神经发育水平较正常足月儿显著降低,极低出生体重、低血糖、父母文化程度低是影响其神经发育的主要因素。
OBJECTIVE: To compare and analyze the differences of neurodevelopment between late preterm infants and normal term infants, and to explore the related factors that affect the neurodevelopmental abnormalities in late preterm infants. Methods: 134 cases of late preterm delivery and 100 full-term infants born in the same period of obstetrics and gynecology obstetrics and gynecology were enrolled in this study. Their general data were collected and tested by developmental providers. Logistic regression analysis was used to screen the neurological parameters of late preterm infants Developmental risk factors. Results: Except for the adaptability and social behavior, the scores of big motor, fine motor, language score and DQ in late preterm group were significantly lower than those in late preterm group (P <0.05). In late preterm group, 9 cases of abnormal neurodevelopment occurred (6.72%), which was significantly higher than that of the control group (1.00%) (P <0.05) .Nerve developmental dysfunction in late preterm infants was closely related to very low birth weight, hypoglycemia and low level of mother’s education. Conclusion: The level of neurological development in late preterm infants is significantly lower than that of normal term infants. Low birth weight, low blood sugar and low educational level are the main factors affecting the neurological development.