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目的：探讨中西医结合在防治断流术后门静脉系统血栓形成的疗效。方法：将97例在我院行脾切断流术的患者分为两组。实验组术后给予丹红注射液与低分子肝素治疗，对照组术后不采用抗凝活血治疗。对比两组术后腹腔引流情况及血小板计数（PLT）、活化部分凝血活酶时间（APTT）、凝血酶原时间（ PT）水平变化。随访6个月观察两组血栓发生情况。结果：两组术后1～4d 腹腔引流量及留管时间对比，差异无统计学意义（P ＞0.05）。两组术后 PLT 水平均显著升高，经统计学处理，差异有统计学意义（Z ＝19.013、18.206， P ＜0.05）。两组间 PLT 水平同期比较，差异无统计学意义（P ＞0.05）。两组手术前后 APTT 和 PT 水平对比，差异无统计学意义（P ＞0.05）。两组间 APTT 和 PT 水平同期比较，差异无统计学意义（P ＞0.05）。随访3个月，实验组血栓发生率（15.15％）显著低于对照组（32.65％）。经统计学处理，差异有统计学意义（χ2＝8.304，P ＜0.05）。结论：断流术后早期给予丹红注射液与低分子肝素治疗，有助于预防门静脉系统血栓的形成，并且不会增加出血的风险。“,”OBJECTIVE: To explore the effect of Tradional Chinese Medicine and Western Medicine in the prevention of portal vein thrombosis after surgery.METHODS: 97 patients underwent splenectomy in our hospital were divided into two groups.The ex-perimental group was treated by low molecular weight heparin.The control group was not treated by anticoagulant therapy.The chan-ges of APTT, PT and PLT levels were compared between the two groups.RESULTS: The remaining of drainage of the two groups af-ter 1 ~4 days was compaired.There was no siginificant difference (P >0.05).The levels of PLT in the two groups were significantly higher.There were statiscally siginificent difference (Z =19.013, 18.206, P >0.05).There were no signifinant difference in the level of PLT (P >0.05).APTT and PT levels were compared before and after operation in the two groups.There were no significant difference (P >0.05).There were no significant difference in the levels of PT in the same period of the two groups (P >0.05). The incidence of thrombosis in the experimental group was significantly lower than that in the control group (32.65%) after 3 months of follow up (15.15%).There was a significant difference ( χ2 =8.304,P <0.05 ).CONCLUSION: Early administration of Danhong injection and low melecular weight heparin after operation in the treatment is helpful to prevent portal venous system thromlosis formation and can not increase the risk of bleeding.