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目的 比较两种粘弹性物质Viscoat和透明质酸钠在白内障超声乳化手术中对角膜内皮的影响。方法 老年性白内障 49人 68眼 ,其中透明质酸钠组 2 5人 3 4眼 ,Viscoat组 2 4人 3 4眼 ,两组患者无内眼病史、眼外伤及眼内手术史 ,无糖尿病等全身疾病史。采用超声乳化术摘出白内障同时植入折叠性人工晶体 ,术前术后用非接触型角膜内皮显微镜观察测量角膜内皮细胞密度。结果 二组一般情况包括年龄 ,晶体核硬度及超声能量与时间的乘积无显著性差异 (P >0 0 5 ) ;透明质酸钠组术前和术后的角膜内皮细胞丢失率为 15 % ,经统计学处理有统计学意义 (P <0 0 5 )。Viscoat组术前和术后的角膜内皮细胞丢失率为 9% ,经统计学处理没有显普性差异 (P >0 0 5 )。结论 在白内障超声乳化手术中粘弹剂Viscoat对角膜内皮细胞的保护能力强于透明质酸钠
Objective To compare the effects of viscoelastic Viscoat and sodium hyaluronate on corneal endothelium during cataract phacoemulsification. Methods A total of 68 eyes with senile cataract were included in this study. There were 34 eyes in 25 cases in sodium hyaluronate group, 34 eyes in 24 cases in Viscoat group, no history of internal eye disease, history of ocular trauma and intraocular surgery, and no diabetes mellitus History of systemic disease. Phacoemulsification cataract extraction with intraocular lens implantation, preoperative and postoperative non-contact corneal endothelial microscopy observation of corneal endothelial cell density. Results There were no significant differences in age, crystal nucleus hardness and ultrasonic energy with time (P> 0.05). The rate of corneal endothelial cell loss in preoperative and postoperative hyaluronic sodium group was 15% Statistically significant (P <0 05). The preoperative and postoperative corneal endothelial cell loss rate in Viscoat group was 9%, which was not statistically significant (P> 0.05). Conclusion Viscoelastic viscoelastic viscoelasto-endothelial keratoplasty is more effective than sodium hyaluronate in phacoemulsification