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至今乙肝表面抗原(HBsAg)的转阴问题已是全世界医学界研究的热点,遗憾的是目前仍无特效的转阴方法。据有关资料统计,我国乙肝带毒者约1 亿多人,孕妇平均每年为1千5百万,其中150万为乙肝病毒携带者,她们的新生儿60％以上被感染。一般HBsAg(+)母亲的婴儿,单接种乙肝疫苗的有效率低于70％,有超过30％的孩子仍有被感染到乙肝的可能。基于此因素,我院自1999年12月至 2004年6月对我院产科孕期发现乙肝表面抗原阳性的母亲及其所分娩的新生儿进行了干预,现将结果报告如下。
To date, the problem of negative conversion of hepatitis B surface antigen (HBsAg) has become a hot spot in the medical field all over the world. Unfortunately, there is still no effective negative conversion method. According to relevant statistics, there are about 100 million people with hepatitis B in our country and the average number of pregnant women is 15 million each year. Of these, 1.5 million are carriers of hepatitis B virus, and more than 60% of their newborns are infected. In general, babies born to HBsAg (+) mothers have an effective rate of less than 70% with hepatitis B vaccine alone, and more than 30% of them still have the possibility of being infected with hepatitis B. Based on this factor, our hospital from December 1999 to June 2004 on our hospital during pregnancy obstetric hepatitis B surface antigen-positive mothers and their birth of newborns were intervened, the results reported below.