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目的了解合肥地区健康人群流脑带菌状况,为制订防控措施提供依据。方法于流脑流行前期采集不同人群咽拭子于卵黄双抗琼脂培养基进行脑膜炎奈瑟氏菌分离培养。结果不同人群共采集标本1047份,检出阳性32份,阳性率3.06%;菌株分别为A,B,C,H,29E群,其中B,C群各占34.4%。高中生组流脑带菌率最高,为6.67%,经统计学检验,与小学生及幼儿组阳性带菌率有显著性差异。男性带菌率3.89%,女性带菌率2.07%,差异无统计学意义;城区人群带菌率2.17%,农村人群带菌率4.24%,差异无统计学意义。结论合肥市健康人群流脑带菌率较低,高中生组人群中流脑带菌率较高。要警惕C群流脑菌群引起的流行,进一步探讨B群带菌率增多的流行病学意义。
Objective To understand the status of streptococcal carriage in healthy population in Hefei and to provide evidence for the development of prevention and control measures. Methods Different groups of throat swabs were collected in early stage of epidemic of meningococci to separate and culture Neisseria meningitidis in yolk double agar medium. Results A total of 1047 samples were collected from different populations. 32 samples were positive and the positive rate was 3.06%. The strains were A, B, C, H and 29E, of which B and C accounted for 34.4%. The prevalence of meconium-borne high-school students was 6.67%. There was a significant difference in the prevalence of positive-carrying bacteria between the high school students and the young children after statistical tests. The carrying rate of males was 3.89% and the carrying rate of females was 2.07%. The difference was not statistically significant. The carrying rate of urban residents was 2.17%, and that of rural residents was 4.24%. The difference was not statistically significant. Conclusion The prevalence of meningitis in healthy population in Hefei City is relatively low, and the prevalence of meningitis in high school students is higher. To guard against the epidemic caused by meningococcal group C, to further explore the epidemiological significance of B group with increased bacterial load.