目的　探讨伪膜性肠炎 (PMC)的临床表现及内镜特征。方法　对 8例PMC进行回顾性分析。结果　全部患者均在使用广谱抗生素过程中出现腹泻、腹痛、血便等表现。接受结肠镜检 ,提示为PMC ,其中 4例患者粪便中培养出难辨梭状芽胞杆菌。结论　PMC多在应用抗生素后发病。老年人、重病患者及外科大手术后患者为易感人群。结肠镜检查是诊断PMC快速而可靠的方法之一 Objective To investigate the clinical manifestations and endoscopic features of pseudomembranous colitis (PMC). Methods 8 cases of PMC were retrospectively analyzed. Results All patients showed diarrhea, abdominal pain and bloody stools during their use of broad-spectrum antibiotics. Colonoscopy was performed, suggestive of PMC, of ​​which Clostridium difficile was cultured in the faeces of 4 patients. Conclusions PMC mostly develops after applying antibiotics. Elderly people, patients with serious illness and surgical patients after surgery for the susceptible population. Colonoscopy is one of the fast and reliable ways to diagnose PMC