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目的探讨探索慢性阻塞性肺疾病(COPD)对冠状动脉介入治疗患者预后的影响。方法回顾性分析2006年1月至2010年12月在首都医科大学大兴医院住院治疗,明确诊断冠心病并行冠状动脉介入治疗的患者共950例,分成COPD组及非COPD组,COPD组150例,非COPD组800例。记录两组患者基本临床状况及随访期间临床事件情况。结果 COPD组年龄[(69.8±10.2)岁]比非COPD组[(66.1±12.1)岁]更大(P<0.01);同非COPD组相比,COPD组吸烟史、陈旧性心肌梗死、心力衰竭等病史更常见(P<0.05);COPD组射血分数[(51.4±15.2)%]较非COPD组[(54.5±14.3)%]低,具有统计学差异。全因死亡、心源性死亡、复发缺血事件,COPD组均明显高于非COPD组(P<0.05),COPD组1个月内再次住院率、全因住院率明显高于非COPD组。结论 COPD患者有更多的冠心病危险因素,冠状动脉支架置入术后有更高的死亡率及再住院率。
Objective To explore the impact of chronic obstructive pulmonary disease (COPD) on the prognosis of patients undergoing coronary artery intervention. Methods A total of 950 patients admitted to Daxing Hospital of Capital Medical University from January 2006 to December 2010 were retrospectively analyzed. A total of 950 patients were divided into two groups: COPD group, non-COPD group and COPD group. 800 cases of non-COPD group. Record two groups of patients basic clinical status and clinical events during follow-up. Results The COPD group had a significantly higher age (69.8 ± 10.2) years than the non-COPD group (66.1 ± 12.1 years) (P <0.01). Compared with the non-COPD group, the smoking history, old myocardial infarction, (P <0.05). The ejection fraction in COPD group (51.4 ± 15.2%) was lower than that in non-COPD group (54.5 ± 14.3%), with statistical difference. All-cause death, cardiogenic death and recurrent ischemic events were significantly higher in COPD group than those in non-COPD group (P <0.05). Rehospitalization rate within 1 month in COPD group was significantly higher than that in non-COPD group. Conclusion COPD patients have more risk factors for coronary heart disease, higher mortality and rehospitalization after coronary stenting.