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重危病人的病理生理学变化不少是以心血管系和呼吸系之间的互相作用为基础的。疾病和治疗所造成的循环动力学后果,常使病情更复杂,也可能使并发症增多和死亡率上升。以下情况可引起类似的后果,如肺高压和肺血管阻力(PVR)增高、慢性阻塞性肺疾病、肺水潴留而血管内脱水、成人呼吸窘迫综合征(ARDS)或心血管虚脱伴有张力性气胸或血胸。某些治疗方法可能有利于肺功能却有损于循环动力。最常用的方法如PEEP和(或)正压通气、液体负平衡伴有前负荷过分降低、药物治疗,特别是应用支气管扩张药茶碱类具有显著β肾上腺素能效应的,都具有一定危险。
The pathophysiology of critically ill patients varies considerably based on the interaction between the cardiovascular and respiratory systems. The cyclical kinetic consequences of illness and treatment often complicate the condition and may lead to increased complications and increased mortality. The following conditions can cause similar consequences such as elevated pulmonary hypertension and pulmonary vascular resistance (PVR), chronic obstructive pulmonary disease, pulmonary dehydration and endovascular dehydration, adult respiratory distress syndrome (ARDS) or cardiovascular collapse with tension Pneumothorax or hemothorax. Some treatments may benefit lung function but impair circulation power. The most commonly used methods such as PEEP and / or positive pressure ventilation, negative fluid balance with excessive preload reduction, and drug treatment, especially with bronchodilators and theophylline class have significant beta adrenergic effects, are considered dangerous.