本文对48例患肝外胆道和十二指肠乳头肿瘤病人做了53次手术。本病的早期诊断非常困难,以致间接地影响治疗效果。完成根治性手术病人为18%。现代诊断方法—CT、超声、内窥镜、胰胆管 X线造影术,在所有病人中都能显示出肿瘤的病变,局限性肿瘤和无转移的病例,施行根治性手术是合理的,对有扩散的病例则采用能使胆道减压的内窥镜和穿刺方法。 This article performed 53 surgeries on 48 patients with extrahepatic biliary and duodenal papillary tumors. The early diagnosis of this disease is very difficult, so as to indirectly affect the therapeutic effect. 18% of patients completed radical surgery. Modern diagnostic methods—CT, ultrasonography, endoscopy, and pancreaticobiliary X-ray radiography—can show tumor lesions, localized tumors, and metastases in all patients. It is reasonable to perform radical surgery. In the case of spread, endoscopic and puncture methods that allow decompression of the biliary tract are used.