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目的:探讨与阻塞性睡眠呼吸暂停低通气综合征(OSAHS)发生的相关因素。方法:本院在开展长沙市老年人慢性病现状调查及社区规范化防治的推广和普及的研究中，采用多阶段抽样法抽取长沙市雨花区>65岁老年人500例，采用多导睡眠监测仪(PSG)进行睡眠呼吸暂停低通气综合征检测和健康体检指标的收集，共70例达到OSAHS诊断标准，根据患者呼吸暂停低通气指数分为轻度42例，中度16例，重度12例，选择非OSAHS 20例为对照组。比较组间一般资料、PSG水平、动态血糖水平。并对OSAHS患者的动态血糖水平与睡眠呼吸低通气指数进行Pearson相关分析。结果:OSAHS组与对照组BMI、围长比、吸烟史、饮酒史、呼吸暂停次数、最长低通气时间、最低血氧饱和度、仰卧位呼吸暂停通气指数、非仰卧位呼吸暂停通气指数比较差异有统计学意义(n P<0.05)。OSAHS患者的血糖波动幅度与睡眠呼吸低通气指数呈正相关(n P65 years old in Yuhua District of Changsha City were selected by multi-stage sampling method. Polysomnography (PSG) was used to detect sleep apnea hypopnea syndrome and collect physical examination indexes. A total of 70 cases met the diagnostic criteria of OSAHS apnea hypopnea index were divided into mild (42 cases), moderate (16 cases) and severe (12 cases). 20 cases of non OSAHS were selected as control group. The general information, PSG level and dynamic blood glucose level were compared between the two groups. Pearson correlation analysis was performed between ambulatory blood glucose level and sleep apnea hypopnea index in OSAHS patients.Results:There were significant differences in body mass index (BMI), girth ratio, smoking history, drinking history, apnea frequency, longest duration of hypoventilation, lowest oxygen saturation, supine apnea index and non supine apnea index between OSAHS group and control group (n P<0.05). The amplitude of blood glucose fluctuation was positively correlated with sleep apnea hypopnea index (n P<0.05).n Conclusions:Among the many associated factors on OSAHS, BMI and the ratio of neck circumference to length and body position have the most notable influence. Patients with OSAHS are more prone to blood glucose fluctuations, and gradually worsen with the progression of OSAHS. Therefore, we should take targeted intervention measures.