论文部分内容阅读
红霉素系半合成大环酯类抗菌素,该药价格便宜,口服方便,因此是一种常用的抗菌素,由于红霉素碱味苦,在酸性下不稳定,从而影响其在临床上的应用。我所研制的红霉素琥珀酸乙酯(简称E·E·S),既能克服上述缺点,而且副作用少,其疗效优于其他红霉素系列产品,主要用于青霉素耐药或过敏的葡萄球菌、链球菌、肺炎球菌等感染,对白喉和百日咳的治疗也有很好的疗效。因此E·E·S制剂在化脓性球菌感染的治疗上仍占有重要的临床地位。
Erythromycin is a semi-synthetic macrocyclic antibiotics, the drug cheap, oral convenience, it is a commonly used antibiotics, due to erythromycin base bitter, unstable under the acid, thus affecting its clinical application . Erythromycin ethyl succinate (E · E · S) developed by our company not only can overcome the above shortcomings but also has less side effects and has better curative effect than other erythromycin series products, mainly used for penicillin resistance or allergy Staphylococcus aureus, Streptococcus, pneumococcus and other infections, the treatment of diphtheria and pertussis also have a good effect. Therefore, E · E · S preparations in the treatment of pyogenic bacteria still occupy an important clinical position.