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1980年10月至1981年12月,我们用吡喹酮治疗了晚期或有夹杂症的日本血吸虫病患者114例,现将临床观察及随访结果摘要报道于下。对象和方法一、病例选择以历年来因晚期或有夹杂症的日本血吸虫病而缓治者为主要对象。男性58例,女性56例。年龄17～68岁。入院后大便沉淀孵化虫卵或毛蚴阳性者48例;环卵试验环沉率5%以上、有临床症状、肝脾肿大者61例;直肠活检虫卵阳性、无治疗史、有临床症状者5例。晚期血吸虫病(以下简称晚血)20例(伴夹杂症7例),其中腹水7例、巨脾2例、肝脾肿大5例、已切脾者6例。早期血吸虫病伴夹杂症者94例,早、晚期共有夹杂症患者101例(见附表)。
From October 1980 to December 1981, we treated praziquantel in 114 patients with advanced schistosomiasis or schistosomiasis, and we present the summary of clinical observations and follow-up results. Subjects and methods First, the selection of patients Over the years due to advanced or schistosomiasis japonica schizophrenia and the main object of treatment. 58 males and 56 females. Age 17 ~ 68 years old. 48 cases were positive for hatching eggs or miracidia after admission; 5% or more for loop-egg test, clinical symptoms, hepatosplenomegaly were 61 cases; rectal biopsy eggs were positive, no treatment history, clinical symptoms 5 cases. Advanced schistosomiasis (hereinafter referred to as late blood) 20 cases (with complications in 7 cases), of which ascites in 7 cases, 2 cases of splenomegaly, hepatosplenomegaly in 5 cases, 6 cases of splenectomy. Early schistosomiasis with complications in 94 cases, early and late total of 101 cases of patients with complications (see table).