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采用逆转录巢式聚合酶链反应技术检测重型肝炎患者血清ＨＧＶＲＮＡ，并与临床病死率间关系进行了初步探讨。结果发现２２例重肝患者血清标本中检出６例ＨＧＶＲＮＡ阳性，阳性率２７．３％，其中亚急性重型肝炎１１例，ＨＧＶＲＮＡ阳性４例，阳性率３６．４％，慢性重型肝炎１０例，ＨＧＶＲＮＡ阳性２例，阳性率２０．０％，急性重型肝炎１例未检出。ＨＧＶＲＮＡ阳性６例中，死亡１例，死亡率１６．７％，ＨＧＶＲＮＡ阴性１６例中，死亡６例，死亡率３７．５％。表明川北地区亦存在ＨＧＶ感染，ＨＧＶ感染病例病死率较低，预后好
Reverse transcription nested polymerase chain reaction (RT-PCR) was used to detect serum HGVRNA in patients with severe hepatitis and the relationship between serum HGVRNA and clinical mortality was also discussed. The results showed that HGVRNA was positive in 6 of 22 cases with severe hepatitis, the positive rate was 27.3%. There were 11 cases of subacute severe hepatitis and 4 cases of HGV RNA positive, the positive rate was 36.4%, 10 cases of chronic severe hepatitis, HGV RNA positive in 2 cases, the positive rate of 20.0%, 1 case of acute severe hepatitis was not detected. Of the 6 HGV RNA positive cases, 1 died and the mortality rate was 16.7%. Of the 16 HGVRNA negative cases, 6 were dead and the mortality rate was 37.5%. That there is also HGV infection in northern Sichuan, HGV infection cases lower mortality and good prognosis