痛风发病率呈逐年上升趋势,多见于中老年男性,重症者可出现肾功能受损、关节破坏等表现,但在年轻患者中出现严重骨质破坏者少见,我科诊治1例年轻男性患者因痛风致严重骨质破坏,现报告如下。1病历摘要患者男,23岁。因手足关节多发结节伴疼痛3年余于2013年8月17日入院。患者3年余前无明显诱因出现手指各指间关节、双足第一跖趾关节处疼痛,逐渐出现绿豆至蚕豆大灰白色质硬结节,多在夜晚、饮酒、进食海鲜后加重;当地医院诊断为痛风,予以别嘌醇、秋水仙碱、痛风定胶囊治疗,患者服药不规律效果 The incidence of gout is increasing year by year, more common in middle-aged men, severe cases may have impaired renal function, joint destruction and other performance, but in young patients with severe osteoporosis are rare, my diagnosis and treatment of a case of young male patients Gout caused by severe bone destruction, are as follows. 1 medical record Summary Male patient, 23 years old. Due to hand-foot joint multiple nodules with pain more than 3 years in August 17, 2013 admission. Patients with no obvious cause more than 3 years before the finger interphalangeal joint, metatarsophalangeal first metatarsophalangeal joint pain, and gradually appeared mung bean to broad gray hard nodules, mostly at night, drinking, eating seafood increased; local hospital Diagnosis of gout, to be allopurinol, colchicine, gout capsule therapy, patients with medication irregularities