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本文报道16例急性有机磷农药中毒并发脑水肿患者,占同期有机磷农药中毒患者的8.2%.其中年龄>50岁并发脑水肿患者显著增多(P<0.05).本组患者口服有机磷农药剂量<20ml者均未发生脑水肿.口服20～50ml、50～100ml、100～200ml及200ml以上者,脑水肿发年率分别为该组的1.9%、9.5%、26.9%及50%.提示随着口服剂量的增加,脑水肿发生率也增高.本文并探讨了脑水肿发生机理.强调对有机磷农药中毒患者应严密观察,及早发现颅内高压症状,及时给予处理.
This article reports 16 patients with acute organophosphorus pesticide poisoning complicated by cerebral edema, accounting for 8.2% of patients with organophosphorus pesticide poisoning over the same period.Among them age> 50 years old with cerebral edema significantly increased (P <0.05) .This group of patients oral organophosphorus pesticide dose <20ml were not brain edema.Oral 20 ~ 50ml, 50 ~ 100ml, 100 ~ 200ml and 200ml above, the annual rate of brain edema were 1.9%, 9.5%, 26.9% and 50% of the group. Oral dosage increases, the incidence of cerebral edema also increased.This paper also discusses the mechanism of cerebral edema.Physical emphasis on patients with organophosphorus pesticide poisoning should be closely observed, early detection of intracranial hypertension symptoms, and timely treatment.