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大约五十年前便已合成维生素 C,但至今它的生理作用还不很清楚。1911年以来,人们只发现维生素 C 与坏血病有明显关系,因而建议服用定量的维生素 C 来预防坏血病(英国规定每日需要量为45毫克,美国定为60毫克)。但是,波林主张为保持健康需要服用更多的维生素 C。他的观点引起了很大争论。在1970年出版的《维生素 C 与感冒》一书中他主张每天服用1至2克维生素 C,这相当于过去推荐量的20倍。他还论说,大剂量维生素 C 能提高智力商和抑制癌的生长。他提出的理由是:多数动物与人类不同,它们都自己生产大量维生素 C。例如一头与人体重相等的羊每天生产的维生素 C 达13克。
Vitamin C has been synthesized about 50 years ago, but so far its physiological role is not clear. Since 1911, only vitamin C has been found to have a clear relationship with scurvy, it is advisable to take a dose of vitamin C to prevent scurvy (45 mg daily in the United Kingdom and 60 mg in the United States). However, Pauline advocated taking more vitamin C for his health. His point of view caused a great deal of debate. In his 1970 book, Vitamin C and Cold, he argued that taking 1 to 2 grams of vitamin C per day equals about 20 times the recommended amount in the past. He also said that high doses of vitamin C can improve IQ and inhibit cancer growth. His rationale is that most animals, unlike humans, produce large amounts of vitamin C themselves. For example, a human with the same weight of sheep produces 13 grams of vitamin C per day.