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目的探讨珂立苏(肺表面活性物质,pulmonary surfactant,PS)对于足月与近足月新生儿呼吸窘迫综合症患者的疗效。方法将2010年1月-2011年10月我院82例足月与近足月新生儿呼吸窘迫综合症患者随机分为两组,对照组采用常规治疗,观察组在常规治疗基础上给予珂立苏,比较两组患者的疗效及血气情况。结果观察组有效率高于对照组,治疗后PaO2、PaO2/FiO2高于对照组,PaCO2水平低于对照组;机械通气时间、吸氧时间及住院时间均短于对照组,组间差异有统计学意义(P<0.05)。结论珂立苏用于足月与近足月新生儿呼吸窘迫综合症患者能提高治疗有效率,同时可以改善血气情况,减少住院时间。
Objective To investigate the efficacy of Ke Li Su (pulmonary surfactant, PS) on neonatal respiratory distress syndrome in term and near term. Methods From January 2010 to October 2011, 82 patients with neonatal respiratory distress syndrome in our hospital were randomly divided into two groups. The control group was treated with conventional therapy. The observation group was given routine treatment Su, the curative effect and blood gas condition of two groups of patients were compared. Results The effective rate of observation group was higher than that of control group. After treatment PaO2 and PaO2 / FiO2 were higher than those of control group and PaCO2 level was lower than that of control group. Mechanical ventilation time, oxygen inhalation time and hospital stay were shorter than those of control group Significance (P <0.05). Conclusion Coriolis for neonatal respiratory distress syndrome of full-term and near term patients can improve the treatment efficiency, at the same time can improve the blood gas situation and reduce the hospitalization time.