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在脊椎动物中胚层的发育诱导过程中 ,骨形成蛋白 (ｂｏｎｅｍｏｒｐｈｏｇｅｎｅｔｉｃｐｒｏｔｅｉｎ ,ＢＭＰ)是重要的背 腹化发育促进因子。ＢＭＰｓ在细胞表面与ＢＭＰ的Ⅰ、Ⅱ型受体相互作用。为研究ＢＭＰｓ信号转导在组织发育和细胞分化中的作用 ,我们以ＢＭＰｓⅡ型突
During the development of vertebrate mesoderm, bone morphogenetic protein (BMP) is an important pro-developmental promoter of dorso-ventral development. BMPs interact with type I and type II receptors on the cell surface. To study the role of BMPs in tissue development and cell differentiation, we used BMPs type II