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目的探讨和分析依达拉奉联合氯吡格雷治疗脑梗死的40例患者的临床疗效,总结其临床价值。方法回顾性分析具有完整临床资料的2008年10月至2010年10月来我院就诊的脑梗死患者40例,随机分为观察组和对照组两组,每组患者有20例,对照组给予氯吡格雷进行治疗,观察组给予依达拉奉联合氯吡格雷进行治疗,观察和比较观两组不同治疗方法对脑梗死的临床疗效。结果对照组基本痊愈10例,显著进步10例,进步8例,无变化12例,总有效率为70.00%;观察组基本痊愈16例,显著进步10例,进步10例,无变化4例,总有效率为90.00%。经χ2检验,两组患者的疗效具有统计学差异(P<0.05)。观察组疗效优于对照组。结论依达拉奉联合氯吡格雷治疗脑梗死疗效显著,明显优于单纯采用氯吡格雷的治疗效果,安全可靠,是治疗急性脑梗死的有效方法之一,值得临床推广和应用。
Objective To investigate and analyze the clinical efficacy of edaravone combined with clopidogrel in the treatment of 40 patients with cerebral infarction and to summarize its clinical value. Methods A retrospective analysis of 40 patients with cerebral infarction who came to our hospital from October 2008 to October 2010 with complete clinical data was randomly divided into observation group and control group, with 20 patients in each group and control group Clopidogrel for treatment, the observation group was treated with edaravone and clopidogrel for treatment, observed and compared the two groups of different treatment methods for the clinical efficacy of cerebral infarction. Results The control group basically recovered in 10 cases, significantly improved in 10 cases, improved in 8 cases, no change in 12 cases, the total effective rate was 70.00%; observation group basically recovered in 16 cases, significantly improved in 10 cases, improved in 10 cases, no change in 4 cases, The total effective rate is 90.00%. By χ2 test, the two groups of patients with a statistically significant difference (P <0.05). Observation group was better than the control group. Conclusion Edaravone combined with clopidogrel treatment of cerebral infarction significant effect, significantly better than the simple use of clopidogrel treatment, safe and reliable, is an effective treatment of acute cerebral infarction, is worthy of clinical promotion and application.