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口腔鳞状细胞癌(OSCC)5年生存率只有50%,为了减少死亡率,早期、准确的识别肿瘤细胞或可能发展为肿瘤的细胞非常重要,本文收集了21例OSCC,7例纤维瘤,2例鳞状细胞乳头状瘤,1例黑色素沉着病及3例正常口腔粘膜新鲜标本,丙酮固定,作冰冻切片,用单克隆抗体17.13(MAb17.13,一种带K轻链的IgM)兔疫组化染色(ABC法)。结果:21例鳞癌反应一致,均阳性(敏感性达100%),个别肿瘤细胞
The 5-year survival rate of oral squamous cell carcinoma (OSCC) is only 50%. To reduce mortality, it is very important to accurately and early identify tumor cells or cells that may develop into tumors. This paper collected 21 cases of OSCC and 7 cases of fibroids. 2 cases of squamous cell papilloma, 1 case of melanotic pigmentation and 3 cases of normal fresh oral mucosa specimens, fixed with acetone, frozen section, with monoclonal antibody 17.13 (MAb17.13, a K-chain IgM) rabbit Epidemic histochemical staining (ABC method). Results: 21 cases of squamous cell carcinoma were consistent, all positive (sensitivity up to 100%), individual tumor cells