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有关SCE率变化的生物学意义至今仍不明了,尽管有人认为不均等SCE可能导致基因的扩增,但SCE变化是否与细胞的增殖和分化有关,现仍不清楚。总结应用BrdU-SCE方法十多年来的工作,特别是我们自己工作的结果,我们得出一个印象:SCE
The biological significance of the change in the SCE rate is still unknown. Although it is thought that inhomogeneous SCE may lead to gene amplification, it is still unclear whether SCE changes are related to cell proliferation and differentiation. Summarizing the work of the BrdU-SCE approach over a decade, especially the results of our own work, we came to an impression: SCE