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ABC免疫酶染色法证实单克隆抗体RS4对胃癌细胞有阳性反应。除对结肠癌、小细胞肺癌及舌瘤有弱阳性交叉反应外,对肝、肺癌等各种细胞株均无反应,免疫组化表明:RS4对各类胃癌的阳性率为70%(42/60),其高分化腺的阳性率达100%,与其他非胃癌恶
ABC immunostaining assay confirmed the positive response of monoclonal antibody RS4 to gastric cancer cells. Except for weak positive cross reaction to colon cancer, small cell lung cancer and tongue tumor, it did not respond to various cell lines such as liver and lung cancer. Immunohistochemistry showed that the positive rate of RS4 to various types of gastric cancer was 70% (42/ 60) The positive rate of well-differentiated glands reaches 100%, compared with other non-gastric cancers.