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目的探讨桥本氏甲状腺炎合并甲状腺癌的临床特点。方法回顾性分析26例桥本氏甲状炎合并甲状腺癌患者的临床特点。结果共收集桥本氏甲状腺炎病例152例,其中合并甲状腺癌26例,发病率为17.1%(26/152)。甲状腺癌患者均先行外科手术治疗,部分术后行131I治疗,并长期口服左甲状腺素片,随访5个月至5年。1例局部复发,2例出现颈部淋巴结转移,均行2次手术,无死亡病例。结论桥本氏甲状腺炎合并甲状腺癌患者缺乏特异性临床症状,通过彩色多普勒超声检查、同位素扫描、甲状腺相关抗体测定及穿刺活检的综合检查可显著提高诊断的准确率。
Objective To investigate the clinical features of Hashimoto’s thyroiditis complicated with thyroid cancer. Methods A retrospective analysis of 26 cases of Hashimoto’s thyroiditis with thyroid cancer in patients with clinical features. Results A total of 152 cases of Hashimoto’s thyroiditis were collected, of which 26 cases were complicated with thyroid cancer, the incidence rate was 17.1% (26/152). Thyroid cancer patients were surgically treated, some 131I treatment after surgery and long-term oral levothyroxine tablets, followed up for 5 months to 5 years. 1 case of local recurrence, 2 cases of cervical lymph node metastasis, performed 2 operations, no deaths. Conclusion Hashimoto’s thyroiditis complicated with thyroid cancer patients lack of specific clinical symptoms, the diagnostic accuracy can be significantly improved by color Doppler ultrasonography, isotope scan, thyroid-related antibody assay and biopsy.