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目的探讨人乳头状瘤病毒(HPV)检测、液基细胞学检测(TCT)与宫颈活检在筛查宫颈病变中的优劣。方法对患者分别进行此三种检测。结果TCT患者中阳性率为3.2%(71/2 221),HPV-DNA检测患者阳性率13.62%(47/345)。HPV-DNA的阳性检出率高于TCT,其差异有统计学意义(P<0.01)。结论三者检测相结合,能明显提高诊断的正确性。
Objective To investigate the advantages and disadvantages of human papillomavirus (HPV) test, liquid-based cytology test (TCT) and cervical biopsy in screening cervical lesions. Methods Patients were tested separately for these three tests. Results The positive rate of TCT patients was 3.2% (71/2 221), and the positive rate of HPV-DNA test was 13.62% (47/345). The positive rate of HPV-DNA was higher than TCT, the difference was statistically significant (P <0.01). Conclusion The combination of the three tests can significantly improve the diagnostic accuracy.