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目的 回顾性分析 98例急性心肌梗死 (AMI)患者入院 2 4h内QTc离散度 (QTcd)变化情况及其与AMI预后的关系。方法 动态观测AMI患者入院时 ,入院后 2、6、2 4h的QTcd ,并在不同组间进行对照分析。结果 在不同的时段恶性心律失常组与非恶性心律失常组及死亡组与存活组QTcd差异显著 (P <0 .0 1) ;恶性心律失常组又分死亡组和存活组 ,入院时两组间QTcd差异无显著性 (P >0 .0 5) ,但入院后各时段两组间QTcd差异显著 (P <0 .0 1) ,且同组 2h后所测到的最小QTcd与入院时QTcd比较 ,前者差异显著 (P <0 .0 1) ,后者差异无显著性 (P >0 .0 5)。结论 AMI患者入院 2 4h内QTcd持续较高 ,下降缓慢者易发生恶性心律失常 ,病死率高
Objective To retrospectively analyze the changes of QTcD (QTcd) in 98 patients with acute myocardial infarction (AMI) within 24 hours after admission and its relationship with the prognosis of AMI. Methods The QTcd of patients with AMI at admission, 2, 6, 24 h after admission were dynamically observed and compared among different groups. Results There were significant differences in QTcd between malignant arrhythmia group and non-malignant arrhythmia group and between death group and survival group at different time points (P <0.01). Malignant arrhythmia group was divided into death group and survival group. There was no significant difference in QTcd between two groups (P> 0.05), but there was a significant difference in QTcd between the two groups after admission (P <0.01). The QTcd measured after 2h in the same group was significantly higher than QTcd at admission , The former significant difference (P <0. 01), the latter was no significant difference (P> 0.05). Conclusions QTcd in patients with AMI within 24 hours after admission was consistently high, and those with slow decline were susceptible to malignant arrhythmia with high mortality